IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel

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IgE-mediated hypersensitivity reactions to cannabis in laboratory personnel.

BACKGROUND There have been sporadic reports of hypersensitivity reactions to plants of the Cannabinaceae family (hemp and hops), but it has remained unclear whether these reactions are immunologic or nonimmunologic in nature. OBJECTIVE We examined the IgE-binding and histamine-releasing properties of hashish and marijuana extracts by CAP-FEIA and a basophil histamine release test. METHODS T...

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Hypersensitivity reactions to metal implants: laboratory options

BACKGROUND All implant compounds undergo an electrochemical process when in contact with biological fluids, as well as mechanical corrosion due to abrasive wear, with production of metal debris that may inhibit repair processes. None of the commonly-used methods can diagnose implant allergies when used singly, therefore a panel of tests should be performed on allergic patients as pre-operative ...

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Upregulation of calprotectin in mild IgE-mediated ovalbumin hypersensitivity

Calprotectin, also known as S100A8/A9, has been linked to gut inflammation caused by IgE-mediated food hypersensitivities, but the pathophysiologic abnormalities it causes remain to be determined. We created a mild food hypersensitivity model through oral gavage of ovalbumin in Norway brown rats without using immune adjuvant. Changes in the levels of calprotectin and inflammation-associated cyt...

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Hypersensitivity reactions to metronidazole.

BACKGROUND Hypersensitivity reactions to metronidazole are infrequently described. However, we believe that such reactions are increasing due to growing use of the drug for the treatment of amebiasis and anaerobe infections combined with other antibiotics. The present study assesses the need for oral provocation in patients with probable hypersensitivity reactions to metronidazole. METHODS We...

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Transfer of IgE-mediated hypersensitivity with autologous stem cell transplantation.

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ژورنال

عنوان ژورنال: International Archives of Allergy and Immunology

سال: 2011

ISSN: 1423-0097,1018-2438

DOI: 10.1159/000324444